| Abstrakt: |
A recent study conducted by researchers at the University of Bologna in Cesena, Italy, focused on the integration of electrophysiology and cardiomechanics in human atrial cardiomyocytes. The study highlighted the role of mechano-electric regulations in cardiac performance and the impact of mechano-calcium and mechano-electric feedback pathways on cardiomyocyte contractile force. The developed mathematical model simulated various physiological responses, such as Ca2+ transient peak and twitch, and suggested potential mechanisms involved in atrial fibrillation. The research concluded that the model could pave the way for future studies on human atrial electromechanics. [Extracted from the article] |
