Research Reports from University of South Florida Provide New Insights into Mononuclear Phagocyte System (Determining the Feasibility of a Cadmium Exposure Model to Activate the Inflammatory Arm of PANoptosis in Murine Monocytes).

Předmět:	BONE marrow cells MONONUCLEAR leukocytes MYELOID cells RETICULO-endothelial system BLOOD cells
Zdroj:	Drug Week; 10/29/2024, p1841-1841, 1p
Abstrakt:	A recent study from the University of South Florida explores the impact of cadmium exposure on the inflammatory arm of PANoptosis in murine monocytes. Cadmium accumulation from cigarette smoking can lead to chronic diseases affecting various organ systems. The study highlights the inflammatory mechanisms of PANoptosis and the role of gasdermin proteins in releasing inflammatory cytokines. Researchers found that cadmium exposure increased the expression of cleaved gasdermin D and E in murine monocytes, leading to dose-dependent cytotoxicity. For more information, the full article is available in the International Journal of Molecular Sciences. [Extracted from the article]
Databáze:	Complementary Index
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