Research from St. Joseph's University Medical Center Reveals New Findings on Lesch-Nyhan Syndrome (A rare occurrence of xanthine urolithiasis in siblings with Lesch-Nyhan syndrome treated with Allopurinol-a case report).

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Zdroj: Drug Week; 10/29/2024, p1919-1919, 1p
Abstrakt: Research from St. Joseph's University Medical Center explores the occurrence of xanthine urolithiasis in siblings with Lesch-Nyhan syndrome treated with Allopurinol. The study highlights the challenge of balancing hyperuricemia treatment with preventing xanthine urolithiasis. Patients with Lesch-Nyhan syndrome may develop xanthine stones in addition to urate stones when treated with Allopurinol, necessitating careful monitoring and dose adjustments. This case report underscores the importance of considering potential complications in patients undergoing Allopurinol treatment for hyperuricemia. [Extracted from the article]
Databáze: Complementary Index