A COMPARATIVE STUDY ON ABG ANALYSIS IN SEVERE ACUTE BRONCHIAL ASTHMA AND CHRONIC BRONCHIAL ASTHMA.

Autor: Mamilla, Rakesh, S., Sarah Nightingale, Lavanya, Y., Suhasini, Sanda, Keerthi, Lanka, Kadam, Charulata Chandrakant
Předmět:
Zdroj: Journal of Cardiovascular Disease Research (Journal of Cardiovascular Disease Research); 2024, Vol. 15 Issue 9, p1802-1808, 7p
Abstrakt: Introduction: Asthma is a chronic inflammatory condition affecting the airways, characterized by an exaggerated response of the trachea-bronchial system to various stimuli. This condition leads to significant narrowing of the airways, which can be alleviated through medication or may resolve spontaneously Therefore, this study focuses on arterial blood gas analysis in patients experiencing acute severe asthma and chronic bronchial asthma upon hospital admission, with particular attention to acid-base status, PaO2, PaCO2, and HCO3- levels. Aim and Objectives: To compare arterial blood gas analysis of acute severe bronchial asthma with chronic bronchial asthma. Materials and Methods: A cross-sectional study was conducted involving 50 asthmatic patients aged between 20 and 75 years, who presented at a tertiary care hospital over a 12-month period. The study excluded pregnant women, children, smokers, and individuals with other respiratory conditions. The entire procedure was thoroughly explained to each patient, and informed consent was obtained. Results: P-value for comparison pf Ph in between the groups was <0.05 which was statistically significant in between the groups. P-value for comparison of mean PaCO2 levels in between the groups was <0.05 which is statistically significant in between the groups. P-value for comparison if PaO2levels in between the groups was > 0.05 which was statistically insignificant in between the groups. Conclusion: It is important to note that arterial blood gas analysis alone does not adequately reflect the severity of an asthma attack; it should be supplemented with further assessments, including Peak Expiratory Flow Rate (PEFR) and Forced Expiratory Volume in one second (FEV1), in conjunction with a clinical evaluation of signs and symptoms. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index