The Modified Triple Test- A Diagnostic Approach to Palpable Breast Lumps.

Autor: M. G., Lokesh, Chandrashekar, S., M. R., Arpitha, Shetty, Dushyanth, Shetty, Manish, M., Thriweni
Předmět:
Zdroj: Journal of Cardiovascular Disease Research (Journal of Cardiovascular Disease Research); 2024, Vol. 15 Issue 9, p97-103, 7p
Abstrakt: Background: In India, breast carcinoma is the 2nd most common malignancy in women. Incidence increases every year which ranges approximately 20-32%. Incidence of breast cancer shows "AGE SHIFT" over the past twenty years in India that is incidence increased from 6 to 17% in the age group of 30-40 years. The 'Modified Triple Test' utilizes-Physical Examination, Ultrasonography of the breast as the radiological method, and FNAC for the diagnosis of palpable breast lumps. It is gaining acceptance with the recent advances in technology and refinements in the interpretative criteria of sonographically characterized masses. Methods A prospective cross sectional study of 50 female patients attending the out patient department of General Surgery, K.R. Hospital, Mysore, between March 2022 to January 2024, with the complaint of a palpable lump/lumps in the breast was undertaken. Results Most commonly affected age group being 30-39 years. Incidence increased from 7 to 16% between the age group of 30 and 40 years. The calculated P - value for parity study is 0.017 and it is shown that malignancy is common among nulliparous. For the menstrual status, the calculated p-value is 0.044 is significant. The breast tumor is common at left side account for about overall 54% age. Fibroadenoma is the most common benign tumor. It was inferred from the study that clinical examination has a sensitivity of 87.5% which means that around 12.5% of the breast carcinoma cases are missed clinically. Results of Modified Triple Test were Sensitivity: 100%, Specificity: 97.37%, PPV: 91.67%, NPV: 100%. Hence the modified triple test can be used as a reliable and fairly accurate means of diagnosis of breast carcinoma. Conclusion Our results show that the diagnostic accuracy of physical examination breast USG and FNA/CNB combined is comparable to that of histological examination. Ultrasound replacing mammography serve as an effective imaging modality in palpable breast lumps and is also more comprehensive. CNB is a suitable alternative when FNA is inconclusive, also offers additional information. Thus the use of MTT to complement findings in differential diagnosis of a lesion in a symptomatic women seeking medical care deserves acceptance and further evalution. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index