| Autor: |
Hoque, Injamam Ul, Debnath, Saradindu, Lo, Rabindranath, Maity, Soumitra |
| Předmět: |
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| Zdroj: |
Chemical Communications; 11/4/2024, Vol. 60 Issue 85, p12429-12432, 4p |
| Abstrakt: |
An expedient route to 2-aminodihydrothiophenes and their seleno analogues is reported. A three-component photoredox reaction between alkene, thio(seleno)cyanate, and bromomalonate is employed, generating a carbo-thio(seleno)cyanate intermediate that undergoes a domino of reactions mediated by alumina column chromatography, leading to valuable chalcogen pharmacophores. Mechanistic investigations using DFT and control experiments reveals an intramolecular H-bond responsible for driving the domino forward. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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