A Randomized Controlled Trial of Ropivacaine Alone and In Combination with Dexamethasone for Oblique Subcostal Transversus Abdominis Plane (OSTAP) Block in Open Cholecystectomy.

Autor: Aruna, Kiran, Shashi, Bansal, Anand Rai, Anshul, Rohilla, Kanika, Yadav, Manoj
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Zdroj: Indian Journal of Surgery; Aug2024, Vol. 86 Issue 4, p724-729, 6p
Abstrakt: Recent randomized trials indicate that oblique subcostal transversus abdominis plane block provides effective analgesia in upper abdominal surgery. Addition of dexamethasone to local anesthetic agent increases its analgesic efficacy. In this randomized, double-blind trial, sixty patients undergoing open cholecystectomy were allocated to two groups. After induction of anesthesia, group R received oblique subcostal transversus abdominis plane block with 18 ml of 0.75% of ropivacaine and 2 ml of normal saline, while 18 ml of 0.75% ropivacaine with 2 ml of dexamethasone was administered in group RD. The primary outcome assessed was total tramadol consumption postoperatively. Secondary outcomes included time to first request for tramadol, sedation score, nausea score, requirement of rescue antiemetics, any side effects, and quality of healing. The total amount of tramadol consumption was significantly lower in group RD as compared to group R (p = 0.009). The time to first request for tramadol was also significantly increased in group RD as compared to group R (p < 0.001). Amount of antiemetics required in group R was more than group RD, and the difference in the requirement was statistically significant (p = 0.017). Oblique subcostal transversus abdominis plane block is effective in providing postoperative pain relief following open cholecystectomy. Addition of dexamethasone to ropivacaine prolongs analgesic efficacy of ropivacaine. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index
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