Privacy enhancing and generalizable deep learning with synthetic data for mediastinal neoplasm diagnosis.
| Autor: | Zhou, Zhanping, Guo, Yuchen, Tang, Ruijie, Liang, Hengrui, He, Jianxing, Xu, Feng |
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| Předmět: |
DATA security
CLINICAL medicine MEDICAL information storage & retrieval systems DIAGNOSTIC imaging DATABASE management DIFFUSION of innovations RESEARCH funding PRIVACY DATA security failures COMPUTED tomography CANCER patients DESCRIPTIVE statistics HOSPITALS MEDIASTINAL tumors DEEP learning COMMUNICATION TECHNOLOGY DIGITAL image processing INDIVIDUALIZED medicine DATA analysis software MEDICAL ethics |
| Zdroj: | NPJ Digital Medicine; 10/20/2024, Vol. 7 Issue 1, p1-15, 15p |
| Abstrakt: | The success of deep learning (DL) relies heavily on training data from which DL models encapsulate information. Consequently, the development and deployment of DL models expose data to potential privacy breaches, which are particularly critical in data-sensitive contexts like medicine. We propose a new technique named DiffGuard that generates realistic and diverse synthetic medical images with annotations, even indistinguishable for experts, to replace real data for DL model training, which cuts off their direct connection and enhances privacy safety. We demonstrate that DiffGuard enhances privacy safety with much less data leakage and better resistance against privacy attacks on data and model. It also improves the accuracy and generalizability of DL models for segmentation and classification of mediastinal neoplasms in multi-center evaluation. We expect that our solution would enlighten the road to privacy-preserving DL for precision medicine, promote data and model sharing, and inspire more innovation on artificial-intelligence-generated-content technologies for medicine. [ABSTRACT FROM AUTHOR] |
| Databáze: | Complementary Index |
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