Endocrine-disrupting chemicals, reproductive aging, and menopause.

Autor: Inman, Zane Cutright, Flaws, Jodi A.
Předmět:
Zdroj: Reproduction; Nov2024, Vol. 168 Issue 5, p22-31, 10p
Abstrakt: Menopause marks the end of a woman's reproductive lifetime and can have a significant effect on a woman's quality of life. Menopause naturally occurs at 51 years of age on average, but recent literature suggests that endocrine-disrupting chemicals (EDCs) in our environment can accelerate reproductive aging, causing women to reach menopause at earlier ages. This is concerning as menopause can significantly alter a woman's quality of life and is associated with increased risks of conditions such as depression, osteoporosis, and cardiovascular disease. EDC exposures have also been associated with more intense menopausal symptoms, making the menopausal transition more difficult for some women. This review highlights the associations between EDC exposure, early menopause, and reproductive aging, using both epidemiological and experimental studies. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index