Lead optimisation of OXS007417: in vivo PK profile and hERG liability modulation to optimise a small molecule differentiation agent for the potential treatment of acute myeloid leukaemia.

Autor: Cogswell, Thomas J., Josa-Culleré, Laia, Zimmer, David, Galan, Sébastien R. G., Jay-Smith, Morgan, Harris, Kate S., Bataille, Carole J. R., Jackson, Thomas R., Douzi Zhang, Davies, Stephen G., Vyas, Paresh, Milne, Thomas A., Wynne, Graham M., Russell, Angela J.
Zdroj: RSC Medicinal Chemistry; Oct2024, Vol. 15 Issue 10, p3495-3506, 12p
Databáze: Complementary Index