New Findings from University of Pittsburgh in the Area of Liver Fibrosis Reported (Inhibition of Heme-thiolate Monooxygenase Cyp1b1 Prevents Hepatic Stellate Cell Activation and Liver Fibrosis By Accumulating Trehalose).
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| Zdroj: | Gastroenterology Week; 10/21/2024, p1198-1198, 1p |
| Abstrakt: | Researchers at the University of Pittsburgh have discovered that inhibiting the heme-thiolate monooxygenase CYP1B1 can prevent hepatic stellate cell activation and liver fibrosis by accumulating trehalose. This finding suggests potential therapeutic strategies for liver fibrosis, particularly in males. The study highlights the role of CYP1B1 in liver fibrosis and the potential benefits of trehalose or its derivative lactotrehalose in treating the condition. [Extracted from the article] |
| Databáze: | Complementary Index |
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