Multidrug-Resistant Organisms Infection on Mortality of Burn Patients at Public Hospital X in Jakarta: A Retrospective Study.
| Autor: | Veronica, Raja Merlinda, Kumalawati, July, Rumende, Cleopas Martin, Nainggolan, Leonard, Simadibrata, Marcellus, Shatri, Hamzah, Yunir, Em, Wardhana, Aditya, Nelwan, Erni Juwita, Rustam, Musfardi |
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| Předmět: |
BURNS & scalds complications
INFECTION risk factors PUBLIC hospitals RISK assessment DRUG resistance in microorganisms SCIENTIFIC observation QUESTIONNAIRES HOSPITAL mortality MULTIDRUG resistance RETROSPECTIVE studies DESCRIPTIVE statistics MULTIVARIATE analysis INFECTION AGE distribution BURN patients LONGITUDINAL method ODDS ratio MEDICAL records ACQUISITION of data INTENSIVE care units CONFIDENCE intervals LENGTH of stay in hospitals COMORBIDITY |
| Zdroj: | Kesmas: National Public Health Journal; 2024 Special Issue, Vol. 19, p76-83, 8p |
| Abstrakt: | Susceptibility to infection and increasing antibiotic resistance put burn patients at risk of developing infections caused by multidrug-resistant organisms (MDRO). This condition can progress to sepsis, increasing morbidity and mortality. This retrospective cohort study employed the medical record data of patients treated at Public Hospital X in Jakarta, Indonesia, from January 2020 to June 2022. Of 160 subjects, most were aged <60 years (82.5%) and had comorbidities (16.88%). The most common cause of burns was fire (86.25%). The use of medical devices was 90.63%, with a 14-day median length of stay. The most common gram-negative MDRO pathogens were K. pneumoniae (29.91%), Enterobacter sp (22.32%), and Acinetobacter (20.54%); 45% of patients infected with MDRO died. The bivariate analysis found an increased risk of death due to MDRO infection in burn patients (RR 1.103; 95%CI 1.004-1.211, p-value = 0.046). After adjusting for role variables (age, comorbidities, total body surface area, use of medical devices, length of stay) and from multivariate analysis, the confounding variables for MDRO infection and mortality were length of stay and age. MDRO infection increases the mortality rate in burn patients. Mortality in burn patients due to MDRO infection is greater than non-MDRO. [ABSTRACT FROM AUTHOR] |
| Databáze: | Complementary Index |
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