A rare case of an EBV-positive inflammatory follicular dendritic cell tumor of the spleen.

Autor:	Eid, Mira Khaldoun, AlQaqaa, Ahmed Samer, Mohammed, Ibraheem J, Shahait, Awni D
Předmět:	FOLLICULAR dendritic cells MAGNETIC resonance imaging COMPUTED tomography SPLEEN SMOOTH muscle
Zdroj:	Journal of Surgical Case Reports; Sep2024, Vol. 2024 Issue 9, p1-3, 3p
Abstrakt:	Epstein–Barr virus positive inflammatory pseudotumor follicular dendritic cell sarcoma (EBV+ FDCS) is a rare indolent neoplasm that presents primarily in the spleen and liver. We display a case of EBV+ FDCS in the spleen, its clinic-pathologic properties, and treatment. Our patient was evaluated following an incidental finding of a splenic mass on imaging after a traumatic injury. Computed tomography and magnetic resonance imaging both confirmed a well-circumscribed lesion in the spleen. Consequently, the patient underwent a robotic-assisted diagnostic splenectomy. Histologic examination revealed portions of spleen with partial effacement of tissue architecture by a well-circumscribed nonencapsulated mass displaying atypical, spindled cells—positive for EBER (CISH), EBV LMP1, smooth muscle actin, and clusterin—mixed inflammatory elements, and interspersed small lymphocytes. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
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