| Autor: |
Kang, Kyung Won, Lemos Barboza, Adriana Lucila, Azpeitia, Leticia Anahí, Gervasi, Claudio Alfredo, Blasetti, Nahuel, Mayocchi, Karina Alejandra, Llorente, Carlos Luis |
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| Zdroj: |
Metallurgical & Materials Transactions. Part A; Nov2024, Vol. 55 Issue 11, p4423-4444, 22p |
| Abstrakt: |
Surface properties of dental implant materials, whether they are physical, chemical, mechanical, or biological, influence the processes of osseointegration and the development of the biological seal at the implant-soft tissue interface. In turn, successful occurrence of these steps prevents peri-implant diseases. This goal can be achieved through the application of surface treatments of a bioactive nature leading to an effective implant-bone union. Our work focuses on a thorough characterization of bioactive surface properties obtained through alkaline treatment on two different surfaces used in the dental implant industry, namely, a surface blasted with calcium phosphate particles and a micro-arc anodized surface. The results show that the alkaline treatment modifies the surface properties of both blasted and anodized samples. Modification is related to the formation of a nanoporous amorphous sodium titanate hydrogel that exhibits high bioactivity in an SBF medium. To assess in vitro biocompatibility and bioactivity, a 48-hour cell culture assay was conducted using dental pulp mesenchymal stem cells. All samples demonstrated cell adhesion, growth, and intercellular communication, indicating that the surfaces are biocompatible and non-cytotoxic. However, samples subjected to alkaline treatment exhibited qualitatively superior bioactivity and in vitro behavior and among them, the blasted sample produced the surface with best performance. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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