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| Zdroj: |
Health & Medicine Week; 10/14/2024, p4962-4962, 1p |
| Abstrakt: |
Researchers from the Technical University Munich have conducted a study on the interface between skin and bone cell cultures and microporous titanium samples. The study aimed to address the issue of forming a reliable natural barrier between the surface of the implant and the skin and bone tissues in percutaneous implants for individuals with limb amputation. The researchers used 3D printing and sintering to fabricate small titanium discs with varying pore sizes, and conducted in vitro experiments to evaluate the biological interactions between dermal fibroblasts and osteoblasts. The results showed that micropore sizes ranging from 200 to 500 μm were favorable for dermal fibroblast adhesion, while pore sizes ranging from 400 to 800 μm demonstrated the best results for osteogenic differentiation in osteoblasts. The study concludes that porous titanium structures have high biointegrative properties and personalized implants can be created for optimal integration with both skin and bone tissues. [Extracted from the article] |
| Databáze: |
Complementary Index |
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