Studies from Nanjing University Have Provided New Information about Obesity, Fitness and Wellness (Photoredox-catalyzed c-indolyl/quinolyl Glycosylation From 2-styrylisocyanides and Glycosyl Bromides).

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Zdroj: Drug Week; 10/18/2024, p3019-3019, 1p
Abstrakt: A study conducted at Nanjing University in the People's Republic of China has explored the synthesis of glycosylation products using indole and quinoline structures, which are present in many biologically active molecules. The researchers developed a photoredox strategy for the synthesis of C-indolyl and C-quinolyl glycosides using specific building blocks. This approach offers mild reaction conditions, high alpha-selectivity, and scalability for large-scale reactions. The research enriches the toolbox of heterocyclic glycosylation methods and has potential implications for the development of heteroaryl-based pharmaceuticals. [Extracted from the article]
Databáze: Complementary Index