Comparison of the Effect of 5 and 10% Intranasal Lidocaine Spray on Improving Headache in Patients with Head Trauma Referring to the Emergency Department.
| Autor: | Tabatabaei, Fatemeh, Mellat, Ali, Esmaeili, Alireza, Mohammadkarimi, Naser, Nikouyeh, Mehrnaz |
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| Předmět: |
HEAD injury complications
INTRANASAL administration HEADACHE STATISTICAL sampling BLIND experiment HOSPITAL emergency services TREATMENT effectiveness RANDOMIZED controlled trials SEVERITY of illness index DESCRIPTIVE statistics PAIN management PATIENT satisfaction DATA analysis software HEAD injuries LIDOCAINE |
| Zdroj: | Journal of Advances in Medical & Biomedical Research; May/Jun2024, Vol. 32 Issue 152, p202-208, 7p |
| Abstrakt: | Background & Objective: Headache is a common complaint among traumatic patients referring to the emergency department. To improve headache in these patients, an effective, fast-acting, accessible and inexpensive drug without a significant effect on the level of consciousness and vital signs is highly needed. Materials & Methods: In this double-blind randomized clinical trial (RCT) on patients with head trauma, Group A was given 5% intranasal lidocaine spray while group B was prescribed 10% intranasal lidocaine spray to improve headache. Headache severity was checked based on numeric pain scale (NPS) before drug administration and then at 5, 15, 30 minutes and plus 1 hour post-drug administration, along with patient satisfaction and possible side effects. Finally, the obtained data were analyzed using SPSS 23 software. Results: According to the data, the maximum reduction in headache occurred 5 minutes after the drug administration. There was a significant difference between the two groups in terms of satisfaction (P value = 0.022), where group A had 100% high satisfaction while group B had 87.5% high satisfaction and 12.5% had moderate satisfaction. Of the 80 patients in the study, 3 patients had tearing complications after medication administration, which resolved after 5 minutes, and one case had nasal mucosal anesthesia, which improved after 15 minutes. Conclusion: According to the results of this study, the use of 5% intranasal lidocaine spray is as effective as 10% intranasal lidocaine spray in relieving headache in traumatic patients and was associated with greater satisfaction and fewer complications. [ABSTRACT FROM AUTHOR] |
| Databáze: | Complementary Index |
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