| Autor: |
Li, Meiqiong, Long, Jiaye, Yang, Miyang, Pang, Yingrong, Chen, Baoxiang, Li, Hong |
| Předmět: |
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| Zdroj: |
Gynecologic & Obstetric Investigation; 2024, Vol. 89 Issue 5, p351-362, 12p |
| Abstrakt: |
Introduction: The link between cruciferous vegetables (CVs) and ovarian cancer (OC) is still uncertain. This meta-analysis is intended to investigate the association between CV consumption and the risk of OC, as well as to conduct a dose-response analysis to determine the degree of correlation between them. Methods: We systematically searched PubMed, Web of Science, Embase, and Cochrane Library databases between database creation and October 2023. The present meta-analysis has been duly registered and assigned the registration number CRD42023470299. This study followed the PRISMA guidelines. The statistical analysis was performed using Stata 14.0 software. Results: There were a total of 7 cohort studies and 7 case-control studies with 7,269 cases and 742,952 subjects. The combined relative risk (RR) of the highest intake of CVs was 0.90 (95% confidence intervals [CIs]: 0.84–0.96; I2 = 54.7%; p = 0.007) compared to the lowest intake of CVs. The odds ratio (OR) was 0.97 (95% CIs: 0.86–1.08; p = 0.192) for cohort studies, and the RR was 0.79 (95% CIs: 0.67–0.91; p = 0.167) for case-control studies. The intake of CVs and the risk of OC were linearly correlated. Adding 15 g of CVs to the diet each day decreased the likelihood of developing OC by almost 4% (RR = 0.963, 95% CIs: 0.905–1.025; p = 0.235). Conclusions: Consumption of CVs may be linked to a lower risk of OC. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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