| Abstrakt: |
A recent study conducted at Soochow University in Suzhou, China, has explored the use of a self-assembled type I nanophotosensitizer for imaging-guided targeted phototherapy of glioblastoma (GBM), a primary brain tumor in adults. The researchers developed a low-O2-dependent type I photosensitizer that can cross the blood-brain barrier and target GBM cells. The photosensitizer nanoparticles demonstrated effective photodynamic and photothermal therapy, leading to the suppression of GBM growth in mice. This research presents a potential design strategy for the treatment of hypoxic GBM. [Extracted from the article] |
