New Anemia Research Reported from University Hospital Ioannina (Intact FGF23 and Markers of Iron Homeostasis, Inflammation, and Bone Mineral Metabolism in Acute Pediatric Infections).

Předmět:
Zdroj: Hematology Week; 10/11/2024, p333-333, 1p
Abstrakt: A recent report from University Hospital Ioannina in Greece discusses research on anemia in pediatric infections. The study aimed to evaluate the association between intact Fibroblast Growth Factor 23 (i-FGF23), iron homeostasis, inflammation, and bone mineral metabolism in acute pediatric infections. The study included 79 children, with 26 having bacterial infections, 26 having viral infections, and 27 serving as healthy controls. The findings showed that patients with bacterial infections had a higher prevalence of anemia of inflammation and functional iron deficiency compared to those with viral infections. The study also found correlations between hepcidin levels, i-FGF23 levels, and various parameters related to iron metabolism, inflammation, and fever duration. Further research is needed to understand the role of FGF23 in the hepcidin-ferroportin axis and its potential for diagnosing bacterial infections and mineral metabolism. [Extracted from the article]
Databáze: Complementary Index