Abstrakt: |
A recent report from Ladoke Akintola University of Technology highlights the ongoing issue of malaria in Africa, with Plasmodium falciparum being the main cause of severe cases. The emergence of drug-resistant strains, particularly those associated with the pfcrt gene mutations, has hindered efforts to control malaria. These mutations, such as the K76T mutation, have compromised the effectiveness of chloroquine, a once vital antimalarial drug. The study emphasizes the need for a comprehensive approach to address the challenges posed by these mutations, including enhanced surveillance, innovative drug development, and community education. Continued research and investment are crucial for overcoming resistance and achieving success in malaria control and eradication in Africa. [Extracted from the article] |