Reports Summarize Cryptococcal Meningitis Findings from University of Minnesota (Cerebrospinal Fluid Cytokines and Chemokines Involved In Cytotoxic Cell Function and Risk of Acute 14-day Mortality In Persons With Advanced Hiv and Cryptococcal...).

Předmět:	CENTRAL nervous system infections CENTRAL nervous system diseases MACROPHAGE inflammatory proteins INFLAMMATORY mediators TUMOR necrosis factors
Zdroj:	TB & Outbreaks Week; 10/11/2024, p956-956, 1p
Abstrakt:	A report from the University of Minnesota discusses the role of the immune response in acute mortality of cryptococcal meningitis. The researchers collected cerebrospinal fluid (CSF) from 337 Ugandans with first-episode cryptococcal meningitis and analyzed the levels of cytokines and chemokines. The study found that higher levels of certain proinflammatory and cytotoxicity-associated cytokines and chemokines in the CSF were associated with a decreased risk of acute 14-day mortality. The researchers suggest that further research on cytotoxic cells is needed to improve understanding of immune responses in cryptococcal meningitis. [Extracted from the article]
Databáze:	Complementary Index
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