Abstrakt: |
A study conducted in Zigong, People's Republic of China, examined the expression of serum fibroblast growth factor 23 (FGF23)/anti-aging gene Klotho and helper T lymphocyte (Th) 1/Th2 cytokines in elders with end-stage renal disease (ESRD). The study found that an imbalance in these serum levels was highly predictive of hospital-acquired infection and prognosis in ESRD patients. Abnormal elevations in serum levels of FGF23, IL-10, and IL-4, as well as lower serum levels of Klotho, IFN-g, and IL-2, were associated with a higher risk of infection and poorer prognosis. These findings provide valuable insights into the prediction and management of hospital-acquired infections in ESRD patients. [Extracted from the article] |