Abstrakt: |
A new study on vitiligo, a common skin depigmentation disorder, has been conducted using computational analysis and molecular dynamic simulation. The study focused on the TYR gene, which is associated with albinism and oculocutaneous diseases. The researchers identified a specific mutation in the TYR gene that affects the structure and stability of the tyrosinase protein, leading to the development of vitiligo. The study provides in silico evidence of vitiligo as a protein folding disorder and explores potential drug derivatives for treatment. The research was conducted by Shabir Ahmad Usmani and his team at Khushal Khan Khattak University in Pakistan. [Extracted from the article] |