| Autor: |
Dondi, Francesco, Gazzilli, Maria, Albano, Domenico, Rizzo, Alessio, Treglia, Giorgio, Pisani, Antonio Rosario, Palumbo, Carmen, Rubini, Dino, Racca, Manuela, Rubini, Giuseppe, Bertagna, Francesco |
| Předmět: |
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| Zdroj: |
Medical Sciences; Sep2024, Vol. 12 Issue 3, p36, 13p |
| Abstrakt: |
Background: The prognostic role of imaging with [18F]fluorodeoxyglucose ([18F]FDG) positron emission tomography/computed tomography (PET/CT) in oropharynx cancer (OPC) has been demonstrated in the past. The aim of this study was to assess the prognostic impact of both baseline and post-treatment PET/CT in patients with OPC and treated with chemo- and/or radiotherapy. Methods: The PET/CT parameters of scans performed before and after therapy were collected and analyzed to find significant prognosticators for progression-free survival (PFS) and overall survival (OS). Human papillomavirus (HPV) infection's influence on the prognosis was also taken into account. Results: A total of 66 patients were included in the study. The staging volumetric parameters of PET/CT were significant prognosticators for OS, while the same parameters were affordable predictors for PFS at the restaging evaluation. No significant correlations between HPV infection and PET/CT parameters were reported. Conclusion: The prognostic role of volumetric [18F]FDG PET/CT parameters in patients with OPC was reported. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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