Methemoglobinemia after sodium nitrite poisoning: what blood gas analysis tells us (and what it might not).

Autor: Cappellini, Fabrizio, Fania, Chiara, Di Simone, Loredana, Gaiani, Francesco, Giani, Marco, Casati, Marco
Předmět:
Zdroj: Clinical Chemistry & Laboratory Medicine; Oct2024, Vol. 62 Issue 11, pe244-e246, 3p
Abstrakt: This letter discusses a case of methemoglobinemia caused by sodium nitrite poisoning. The patient exhibited symptoms such as coma, cyanosis, desaturation, and hypotension. The blood gas analyzer used in the emergency department was unable to accurately measure hemoglobin concentration and saturation, which hindered the diagnosis and treatment of the patient. The letter also describes in vitro experiments that were conducted to understand why the analyzer failed to measure methemoglobin levels. The results suggest that the analyzer had difficulty reporting methemoglobin levels accurately, and clinicians should be aware of this issue when treating patients with methemoglobinemia. [Extracted from the article]
Databáze: Complementary Index