Atrophic Kidney-Like Lesion—Case Report and Review of the Literature.

Autor: Wang, Xin, Lovelace, Elizabeth, Pacheco, Richard R., Pacheco, Robert, Schuster, Michael E., Bernstein, Adrien, Akgul, Mahmut, Lightle, Andrea
Předmět:
Zdroj: International Journal of Surgical Pathology; Oct2024, Vol. 32 Issue 7, p1327-1331, 5p
Abstrakt: Atrophic kidney-like lesion (AKLL) is a rare kidney lesion, which was recently suggested by the Genitourinary Pathology Society as a provisional entity. As of now, 16 examples of AKLL have been described in the literature. Here we report a new tumor which shows similar clinicopathologic characteristics with those previously reported in AKLL. Immunohistochemical (IHC) studies in the current lesion identified a biphasic staining pattern consisting of a mixture of WT1+/KRT7-/PAX8- large dilated cysts and WT-/KRT7+/PAX8+ small atrophic cysts. Histomorphologic features of AKLL overlap with several neoplastic and non-neoplastic entities which can lead to mischaracterization. Awareness of the differentiating features is likely important when evaluating these lesions. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index