Synthesis, Characterization, and Docking Study of a Novel Indole Derivative Containing a Tosyl Moiety as Anti-Oxidant Agent.

Autor:	Chihab, Abdelali, El Brahmi, Nabil, El Kazzouli, Saïd
Předmět:	NUCLEAR magnetic resonance INDOLE derivatives MOLECULAR docking INFRARED spectroscopy MASS spectrometry
Zdroj:	Molbank; Sep2024, Vol. 2024 Issue 3, pM1857, 9p
Abstrakt:	Indole derivatives are key components of natural products and possess a wide range of biological and pharmaceutical applications. Here, we present the synthesis of a new indole derivative, namely 2-(1-ethyl-5-nitro-1H-indole-7-carbonyl)butyl 4-methylbenzenesulfonate. The structural elucidation of this compound was accomplished through comprehensive spectroscopic analysis, including Fourier-transform infrared spectroscopy (FTIR), nuclear magnetic resonance (NMR), and high-resolution mass spectrometry (HRMS). Our molecular docking study revealed that this compound exhibits strong affinity towards tyrosinase, making it a promising candidate as an antioxidant agent. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
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