| Autor: |
William, P., Yogeesh, N., Lingaraju, Chetana, R., Vasanthakumar, T. N., Verma, V. |
| Předmět: |
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| Zdroj: |
Journal of Nano- & Electronic Physics; 2024, Vol. 16 Issue 4, p1-5, 5p |
| Abstrakt: |
Protein compositions applied on Engineered Nanomaterials (ENM) require the presence of nanoscale protein molecules for multiple biochemical uses. Potential toxicity hazards and the requirement for full safety evaluations caused by the complex interactions between nanoparticles and biological systems are issues. Effectively Fluorescamine approaches for predicting protein composition on synthetic nanomaterials ENM can clarify biochemical findings from ENMs that are in biological structures without needing long-term protein composition tests. The Polypeptide Chemical Reaction Optimised Resistant Logistic Regression Model (PCRO-RLRM) is an innovative Artificial Intelligence (AI) technology that would be utilized in this research. The protein composition is analyzed using the Z-score normalization technique. The key elements from the normalized data that are useful for studying proteins or amino acid areas are extracted using the Position-Specific Scoring Matrix, or PSSM. Applying Polypeptide Chemical Reaction Optimisation (PCRO) to modify the algorithm's parameters improves the predicted performance of the RLRM method. The findings reveal that the PCRO-RLRM combination is superior to the analysis of Protein Composition algorithm in accuracy (96.57%), sensitivity (94.5%), and specificity (98.03%). This novel approach has the potential to promote findings in biochemistry based on nanomaterials and to improve bioengineering techniques. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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