Microencapsulation of Berberine to Develop a Natural Antibacterial Delivery System for Drinking Water.

Autor: Gizem Şanlıtürk, Mustafa, Faisal Suleiman, Güran, Mümtaz, Doğan, Şifa, Gazi, Mustafa
Předmět:
Zdroj: Journal of Water Chemistry & Technology; Oct2024, Vol. 46 Issue 5, p449-457, 9p
Abstrakt: In this study, we aimed to fabricate a novel, completely natural antibacterial disinfectant material for environmental applications, such as treating drinking water. We created two different berberine−alginate (BerAlg) beads using the ionotropic gelation method, employing calcium and aluminium ions as cross-linkers. The materials were characterized using Fourier-transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), swelling, and release kinetic studies. Antibacterial activity was assessed through time-kill analysis. Among the four release kinetics models tested, the BerAlg bead formulation showed the best fit with the Korsmeyer−Peppas model, having the highest R2 value (0.9757). The longest release of berberine (Ber) was observed over a 4-h period. The time-kill assay results revealed that BerAlg beads were effective in killing for up to 7 h. In conclusion, these results demonstrate the promising potential of BerAlg beads as an antibacterial delivery system for disinfecting various liquid environments, such as drinking water. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index