Sympathetic innervation of interscapular brown adipose tissue is not a predominant mediator of OT-elicited reductions of body weight gain and adiposity in male diet-induced obese rats.

Předmět:	WEIGHT loss BETA adrenoceptors BROWN adipose tissue WHITE adipose tissue SYMPATHETIC nervous system
Zdroj:	Obesity, Fitness & Wellness Week; 9/30/2024, p678-678, 1p
Abstrakt:	A recent study investigated the role of sympathetic innervation of interscapular brown adipose tissue (IBAT) in the weight loss effects of oxytocin (OT) in diet-induced obese (DIO) rats. The researchers hypothesized that the activation of the sympathetic nervous system (SNS) in IBAT contributes to the weight loss effects of OT. However, their findings suggest that sympathetic innervation of IBAT is not necessary for OT to increase brown adipose tissue thermogenesis and reduce body weight gain and adiposity in male DIO rats. This study provides insights into the mechanisms underlying the weight loss effects of OT in obesity. [Extracted from the article]
Databáze:	Complementary Index
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