| Abstrakt: |
A patent application titled "Soluble Guanylyl Cyclase (GC1) Mimetic Polypeptides and Methods of Use Thereof" has been published online by the US Patent and Trademark Office. The patent application, filed by Annie V. Beuve of Rutgers University, describes a construct comprising a polypeptide derived from soluble guanylyl cyclase (GC1) and its potential use in treating diseases and disorders. The construct may be conjugated to a cell penetrating peptide (CPP) and administered as a pharmaceutical composition. The invention aims to inhibit the interaction and complex formation of GC1 and thioredoxin (Trx1), which play a role in NO signaling pathways, apoptosis regulation, and vasodilation. [Extracted from the article] |
