| Abstrakt: |
A recent study conducted in Anhui, People's Republic of China, investigated the calcium-activated chloride channel (CLCA4) in colon adenocarcinoma (COAD) and its association with immune infiltration. The study used various datasets to assess the expression, prognosis, and immune infiltration of CLCA4 in cancer. The findings showed that COAD tissues had lower levels of CLCA4 expression compared to normal tissues, and lower expression levels were associated with worse prognosis. The study also found positive correlations between CLCA4 mRNA expression and copy number variation (CNV), as well as an association between CLCA4 CNV and immune infiltration. Overall, the study suggests that CLCA4 expression impacts the immunological microenvironment and functions related to ion transport, metabolism, and intestinal digestion. [Extracted from the article] |
