Abstrakt: |
A recent study conducted by researchers at the School of Medicine in Galway, Ireland, has found that the human microbiome plays a significant role in the effectiveness and safety of commonly prescribed drugs. The researchers developed a computational model called AGORA2, which incorporates microbial metabolism and can predict the drug conversion potential of gut microbiomes in individuals. The study demonstrated that the drug conversion potential varied greatly between individuals and was influenced by factors such as age, sex, body mass index, and disease stage. This research provides valuable insights into personalized medicine and the metabolic interactions between the human body and its microbiome. [Extracted from the article] |