| Abstrakt: |
A recent study conducted by researchers from the University of Helsinki explores the development of carbohydrate delivery agents for Boron Neutron Capture Therapy (BNCT), a cancer treatment that combines boron delivery agents with thermal neutrons to selectively target and eliminate cancer cells. The researchers synthesized and evaluated a set of fluorinated carbohydrate derivatives and found that they may have advantages over current boron delivery agents in terms of improved boron delivery capacity at the cellular level. However, the carbohydrate delivery agents also exhibited strong binding to plasma proteins, which may require further investigation before progressing to in vivo studies. This research provides valuable insights for the future development of theranostic agents for BNCT based on carbohydrates. [Extracted from the article] |
