| Autor: |
Talib, Aya Fawzi, Khalid, Shahad Sabah, Abd, Mohammed A. |
| Předmět: |
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| Zdroj: |
Iraq Medical Journal (IMJ ); Spring2024, Vol. 8 Issue 2, p45-47, 3p |
| Abstrakt: |
Objective: To investigate the levels of vaspin and C-reactive protein in women with polycystic ovarian syndrome (PCOS) and to assess their potential as diagnostic markers for the condition. Methods: Ninety adult women were involved in the study, fifty of whom were obese women diagnosed with PCOS, while forty women served as healthy controls in an observational, case-control study. Blood samples were obtained from the participants, and all of them were questioned by the researcher. Vaspin and C-reactive protein serum levels were measured using enzyme-linked immunosorbent assay specialized kits. Results: The study found a significant increase in vaspin and C-reactive protein serum levels in women in the PCOS group compared with controls, with P-values of <0.000 and 0.006, respectively. Vaspin serum level showed an AUC of 0.835, indicating it is a very good diagnostic marker for PCOS, while C-reactive protein had an AUC of 0.635, making it a moderate diagnostic marker for PCOS. The study also found a significant correlation between vaspin (pg/ml) and C-reactive protein (mg/l) with a P-value of 0.006. Conclusion: The study found a significant increase in vaspin (pg/ml) and C-reactive protein (mg/l) serum levels in females with PCOS compared to control groups, with a significant positive correlation between the two biomarkers in PCOS. This suggests that vaspin and C-reactive protein may serve as useful diagnostic markers for PCOS. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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