Synthesis and characterization of polyvinyl alcohol/Senna alata extract incorporated film for biomedical application.

Autor: Sridhar, N., Vallavi, M. S. Aezhisai, Mugilan, T.
Předmět:
Zdroj: Polymer Bulletin; Oct2024, Vol. 81 Issue 15, p13839-13862, 24p
Abstrakt: Medicinal plant of Senna alata (S. alata) extract incorporated into Polyvinyl alcohol (PVA) film was successfully synthesized through a solution casting technique. The surface morphology of PVA/S. alata film was characterized by FE-SEM, which revealed the smooth and homogenous surface of the film and indicated the dispersion of S. alata in the PVA matrix. PVA functional group of hydroxyl and principal component of S. alata leaves flavonoids and anthraquinones presented in PVA/S. alata film was confirmed by FTIR spectra. XRD pattern results showed the crystallinity nature of PVA/S. alata film. Thermal analysis (TGA/DTG) demonstrated that incorporating S. alata extract in the PVA matrix enhanced the film thermal stability. In-vitro scratch wound assay was studied for PVA/S. alata film. The maximum wound healing activity of 93% was attained at 24 h with interaction on the mouse fibroblast L929 cell line, and wound gap width was measured through Image J software. Therefore, the developed PVA/S. alata film shows significant potential as an effective wound dressing material. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index