HPLC-UV МЕТОД ЗА ОПРЕДЕЛЯНЕ НА СЪДЪРЖАНИЕТО НА ВОДОРОДЕН ПЕРОКСИД В ИЗБЕЛВАЩИ ПРОДУКТИ ЗА ЗЪБИ.

Autor: Тачев, Антон, Христова-Багдасарян, Валентина, Петрова, Светла
Předmět:
Zdroj: Bulgarian Journal of Public Health; 2024, Vol. 16 Issue 3, p82-89, 8p
Abstrakt: Introduction: Over the last ten years the use of teeth whitening products containing hydrogen peroxide (H2O2) has become popular. According to European legislation, it is allowed to be added to products for both professional and personal use, in concentrations from 0.1 to 6%. Ingestion of low concentrations of hydrogen peroxide in the oral cavity does not lead to adverse effects, but its long-term use can lead to health risks. Aim: Development of a method for the determination of hydrogen peroxide in teeth whitening products. Material and methods: The method is based on the oxidation of hydrogen peroxide with triphenylphosphine (TPP) to triphenylphosphine oxide (TPPO) and the subsequent reverse phase HPLC-UV analysis of TPPO at a wavelength of 255 nm. Results: The method was applied to the analysis of commercial products for personal use containing urea peroxide or sodium percarbonate. Discussion: The results of the analyzed products show compliance of the hydrogen peroxide content with the values in Regulation (EC) No. 1223/2009 of the European Parliament and of the Council of 30 November 2009 on cosmetic products (recast), especially for oral care products - teeth whitening (from 0.1 to 6%). Conclusion: The method is suitable for official control purposes in the working range 30.00 ÷ 180.00 µg of H2O2 per kg product (from 0.08 % to 10% hydrogen peroxide). [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index