| Autor: |
Turan, Muzaffer Onur, Bozkuş, Fulsen, Batum, Özgür, Alkan, Aycan, Kabalak, Pınar Akın, Alkılınç, Ersin, Söyler, Yasemin, Geçkil, Ayşegül Altıntop, Çapraz, Aylin, Arslan, Sertaç, Turan, Pakize Ayşe, Şengül, Aysun, Baykal, Hüsnü, Aydemir, Yusuf, Yazıcı, Onur, Gülhan, Pınar Yıldız, Gülen, Şule Taş, Emre, Jülide Çeldir, Mirici, Arzu |
| Předmět: |
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| Zdroj: |
Eurasian Journal of Pulmonology; May-Aug2024, Vol. 26 Issue 2, p120-127, 8p |
| Abstrakt: |
BACKGROUND AND AIM: Persistent physical and medical sequelae, including chronic hypoxemia, may be observed in patients with long-lasting post-COVID syndrome. Long-term oxygen therapy (LTOT) is commonly employed for managing chronic hypoxemia in chronic airway diseases. This study aims to assess the ongoing requirement for LTOT in Coronavirus Disease 2019 (COVID-19) patients during the post-COVID period and to ascertain the persistence of their oxygen therapy needs. METHODS: This cross-sectional, multicentered study included 320 COVID-19 patients who were evaluated for LTOT two months post-discharge. Patient demographics, symptoms at admission, and laboratory and radiological data were retrospectively collected from hospital databases. RESULTS: Continuous oxygen support was necessary for 22.9% of the patients, while 15% of the participants passed away during the post-COVID period. Factors significantly associated with the prolonged need for LTOT included admission to the intensive care unit (ICU), presence of anemia, high serum D-dimer levels (>1000 μg/L), and low oxygen saturation levels at hospital admission (p=0.026, p=0.011, p=0.010, and p<0.001, respectively). Multivariable regression analysis identified high D-dimer levels (p=0.012) and low oxygen saturation at admission (p<0.001) as the most significant predictors of a continued need for oxygen therapy. Furthermore, advanced age, non-use of steroids in treatment, and mechanical ventilation during hospitalization were significantly linked to mortality during the post-COVID period (p=0.003, p=0.048, and p=0.009, respectively). CONCLUSIONS: ICU admission and certain laboratory parameters can predict the need for LTOT during the post-COVID process. The observation that most COVID-19 patients do not require LTOT after a two-month period suggests that clinicians should adopt a more selective approach in planning LTOT. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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