Compliance with Low-Dose Aspirin and Outcomes in High-Risk Pregnant Women in Guna District of Central India.

Autor:	Sharma, Lalit K., Choorakuttil, Rijo M., Nirmalan, Praveen K.
Předmět:	RISK factors of preeclampsia FETAL growth retardation -- Risk factors INDIAN women (Asians) PATIENT compliance RISK assessment DOPPLER ultrasonography ASPIRIN PREMATURE infants FETAL ultrasonic imaging TREATMENT effectiveness DESCRIPTIVE statistics PRENATAL care ARTERIAL pressure DURATION of pregnancy RURAL population GESTATIONAL age DRUGS BIRTH weight COUNSELING
Zdroj:	Indian Journal of Radiology & Imaging; Oct2024, Vol. 34 Issue 4, p636-639, 4p
Abstrakt:	Aim This article determines the compliance rates with low-dose aspirin (LDA) and outcomes in a group of pregnant women identified at high risk for preeclampsia (PE) and fetal growth restriction (FGR) at 11 to 14 gestational weeks (GWs) in a rural district of central India. Methods A single, experienced fetal radiologist assessed all enrolled pregnant women using trimester-specific antenatal screening protocols that included mean arterial blood pressure assessment, and fetal ultrasound and Doppler studies. A trimester-specific individualized risk for preterm PE and FGR was estimated for each woman. Pregnant women categorized as high risk for preterm PE or FGR based on a 1 in 150 criteria at 11 to 14 GW were recommended LDA 150 mg once daily at bedtime. Outcome measures included compliance with LDA assessed, incidence of PE and FGR, preterm delivery (<37 GW), birth weight, stillbirths, and perinatal mortality. Results The data of 488 pregnant women with longitudinal trimester-specific assessments from 11 to 14 GW till childbirth was analyzed. At the third trimester assessment, 215 (80.83%) of the high-risk women were compliant with LDA. The incidence of PE, FGR, and preterm births was significantly higher in LDA noncompliant women, and the mean birth weight was significantly higher in LDA-compliant high-risk women. Conclusion Good compliance for LDA is possible in rural populations with adequate counseling. Starting LDA at 11 to 14 GW for high-risk pregnant women lowered the incidence of PE, FGR, and preterm birth rates and improved birth weight in the study population. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
Externí odkaz:	Zobrazit plný text záznamu Plný text ve formátu HTML
Nepřihlášeným uživatelům se plný text nezobrazuje	K zobrazení výsledku je třeba se přihlásit.