Synthesis of new chiral arylsulfonamides based on carane amino alcohols.

Autor: Grebyonkina, O. N., Banina, O. A., Rumyantsev, R. V., Baidamshina, D. R., Kolesnikova, A. I., Lezina, O. M., Rubtsova, S. A.
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Zdroj: Russian Chemical Bulletin; Aug2024, Vol. 73 Issue 8, p2238-2247, 10p
Abstrakt: New optically active arylsulfonamides, including carane-containing streptocide analogs, were synthesized by the reaction of carane amino alcohols with tosyl- and N-acetylsulfanilyl chlorides. Sulfonamide, which was prepared based on (–)-4β-amino-3α-hydroxy-cis-carane, was studied by X-ray diffraction. The synthesized sulfonamides and the starting amino alcohols were evaluated for antimicrobial activity. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index