Health risk assessment of heavy metals in Malay herbal medicine (MHM) consumed by pregnant and postpartum mothers.

Autor:	Bustami, Normina Ahmad, Tan, Chung Keat, Lee, Yu Zhao, Zaman, Rahela, Ho, Yu Bin, Aris, Ahmad Zaharin, Sadat, Marjan, Tan, Eugenie Sin Sing
Předmět:	ANALYSIS of heavy metals MISCARRIAGE RISK assessment CROSS-sectional method BREASTFEEDING TRADITIONAL medicine HEALTH status indicators RESEARCH funding T-test (Statistics) HERBAL medicine PUERPERIUM PILOT projects QUESTIONNAIRES FISHER exact test PREGNANT women BREAST milk DESCRIPTIVE statistics CHI-squared test PLANT extracts CHRONIC diseases RESEARCH MASS spectrometry COMPARATIVE studies CONFIDENCE intervals SOCIODEMOGRAPHIC factors DATA analysis software DIETARY supplements DISEASE risk factors PREGNANCY
Zdroj:	Discover Public Health; 9/17/2024, Vol. 21 Issue 1, p1-12, 12p
Abstrakt:	Background: Malay herbal medicine (MHM) is a popular medication and supplementation among Malaysian mothers during pregnancy and postpartum. It is expected to improve the baby's health, increase breastmilk production, promote slimming and uterine involution, and improve the mother's general health. Recent increases in reports of heavy metal contamination have raised safety concerns. Objective: This pilot exploratory study employed a comparative cross-sectional design to investigate the types of MHM ingested during pregnancy and postpartum, their possible heavy metal contamination and associated health risks. Method: This study involved 167 healthy postpartum Malay women. Findings: MHM consumption was significantly associated with the mother's number of pregnancies and children (p < 0.05) as well as her pre-pregnancy weight (p < 0.05). Mothers who consume MHM were twice as likely (95% CI 1.077–3.963) to experience threatened abortion. Heavy metals were detected in the three most widely consumed MHM samples. The mean concentration of heavy metals in these samples were 47.44 ± 67.74 μg/kg for As, 25.34 ± 2.48 μg/kg for Cd, 3685.87 ± 5683.36 μg/kg for Cr and 194.33 ± 195.19 μg/kg for Pb. The calculated non-carcinogenic hazard health risks (HQ) and health index (HI) were less than one, suggesting no adverse health impacts under the exposure conditions studied. Conclusion: While the HQ and HI values indicate no immediate health risks, the potential transfer from mother to foetus during pregnancy and from mother to infant during breastfeeding warrants further investigation. Additional studies are essential to confirm our findings and monitor the health of mothers and infants. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
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