The Global Rise of ESBL-Producing Escherichia coli in the Livestock Sector: A Five-Year Overview.

Autor: Mandujano-Hernández, Antonio, Martínez-Vázquez, Ana Verónica, Paz-González, Alma D., Herrera-Mayorga, Verónica, Sánchez-Sánchez, Mario, Lara-Ramírez, Edgar E., Vázquez, Karina, de Jesús de Luna-Santillana, Erick, Bocanegra-García, Virgilio, Rivera, Gildardo
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Zdroj: Animals (2076-2615); Sep2024, Vol. 14 Issue 17, p2490, 23p
Abstrakt: Simple Summary: Bacteria producing extended-spectrum β-lactamases (ESBLs) have become a critical problem of the 21st century, as they are one of the main causes of resistance to most antibiotics available on the market. This problem not only affects humans, as previously known, but has also escalated to animals, which is alarming, as many of these animals are a part of the daily diet of people worlwide. This study provides relevant information on ESBL-producing bacteria found in farm animals from different regions of the world over the last five years and may become considered an important pillar in the fight against antibiotic resistance. β-lactam antibiotics are a key element in the treatment of bacterial infections. However, the excessive use of these antibiotics has contributed to the emergence of β-lactam-resistant enterobacteria, including Escherichia coli. One of the main challenges facing the public health sector is antibacterial resistance (ABR), mainly due to limited options in its pharmacological treatment. Currently, extended-spectrum β-lactamases (ESBLs) present an alarming situation, as there is an increase in morbidity and mortality rates, prolonged hospital stays, and increased costs for sanitary supplies, which involve not only humans but also the environment and animals, especially animals destined for food production. This review presents an analysis of the prevalence of ESBL-producing E. coli and its distribution in different animal sources throughout the world, providing an understanding of the association with resistance and virulence genes, as well as perceiving the population structure of E. coli. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index
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