| Autor: |
Anjum, Komal, Huang, Xiaofei, Zhou, Luning, Zhu, Tianjiao, Che, Qian, Zhang, Guojian, Li, Dehai |
| Předmět: |
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| Zdroj: |
Natural Product Research; Sep2024, Vol. 38 Issue 18, p3231-3236, 6p |
| Abstrakt: |
A new alkaloid named aspergilalkaloid A (1) with pyridoindole hydroxymethyl piperazine dione structure along with six known compounds 2-7 were isolated from deep-sea derived fungus Aspergillus sp. HDN20-1401. The structure including absolute configuration was elucidated by extensive NMR analyses, HRESIMS, ECD calculation, and theoretical NMR calculation with DP4+ analysis. All isolated compounds were tested for antimicrobial and anticancer activity. Aspergilalkaloid A (1) showed inhibitive activity against Bacillus cereus with MIC value of 12.5 μM and weak activity against MRCNS. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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