Researchers from Southern University of Science and Technology (SUSTech) Detail Findings in Cancer Research (Dissecting Phospho-motif-dependent Shc1 Interactome Using Long Synthetic Protein Fragments).

Předmět:	SYNTHETIC proteins AMINO acid separation SCAFFOLD proteins PEPTIDES PEPTIDOMIMETICS
Zdroj:	Cancer Weekly; 9/17/2024, p1043-1043, 1p
Abstrakt:	Researchers from the Southern University of Science and Technology (SUSTech) in Shenzhen, China, have conducted a study on the role of the scaffold protein Shc1 in directing protein complex formation for receptor tyrosine kinases (RTKs) in cancer cells. The researchers used synthetic protein fragments to analyze the site-specific interactomes of Shc1 and demonstrated that these fragments can be used as a diagnostic tool to assess cell type-specific RTK signaling networks. The study provides insights into the organization and functional roles of Shc1 adaptor protein complexes in cancer. The research was funded by the National Natural Science Foundation of China and other organizations. [Extracted from the article]
Databáze:	Complementary Index
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