New Tuberculosis Data Have Been Reported by Researchers at University of Cape Town (High-dose Isoniazid Lacks Early Bactericidal Activity Against Isoniazid-resistant Tuberculosis Mediated By Katg Mutations a Randomized Phase Ii Clinical Trial).

Předmět:	MYCOBACTERIAL diseases NIACIN MYCOBACTERIUM tuberculosis COMMUNICABLE diseases BACTERIAL genetics MULTIDRUG-resistant tuberculosis
Zdroj:	TB & Outbreaks Week; 9/20/2024, p1099-1099, 1p
Abstrakt:	A recent report discusses research conducted at the University of Cape Town on the efficacy of high-dose isoniazid in treating tuberculosis caused by katG-mutated Mycobacterium tuberculosis (M.tb). The study found that high-dose isoniazid had negligible bactericidal activity against katG-mutated M.tb in the majority of participants. The research suggests that further investigation is needed to determine the effectiveness of high-dose isoniazid in treating multidrug-resistant tuberculosis. The study was funded by various organizations, including the National Institutes of Health in the United States. [Extracted from the article]
Databáze:	Complementary Index
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