| Autor: |
Jamarun, Novesar, Mayasari, Dian, Septiani, Upita, Tricahyani, Nabilla Ayyu, Wulandari, Prasejati, Arika, Amirullah, Tri Yupi |
| Předmět: |
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| Zdroj: |
Rasayan Journal of Chemistry; Jul-Sep2024, Vol. 17 Issue 3, p803-808, 6p |
| Abstrakt: |
Hydroxyapatite (HAp) is the primary inorganic constituent found in bones and teeth. It possesses biocompatibility and bioactivity within the human body, while its mechanical qualities are somewhat inferior. Magnesium is a viable alternative to calcium in the composition of bone minerals. Copper is both an antibacterial agent and a vital metal within our bodies. This study aims to produce Mg, and Cu-HAp by employing the sol-gel process in situ utilising Lokan shell (Geloina. Expansa) as the source material. Additionally, the antibacterial properties of Mg and Cu-HAp will be evaluated. The lokan shell is utilized as a calcium source, containing 94.626% calcium oxide (CaO), for synthesizing hydroxyapatite (HAp) with a calcium-to-phosphorus ratio of 1.67. The X-ray diffraction (XRD) analysis revealed a distinct pattern at a specific angle of 2θ, following the ICDD (No.96-101-1243) standard. The FT-IR spectra suggest that the bending vibration of the PO43- functional group occurs at a wave number of 610 cm-1, whereas the asymmetrical stretching occurs at wave numbers between 1010-1036 cm-1. These observations suggest the presence of HAp content. The antibacterial test results demonstrated that Mg, Cu-HAp3, and Mg, Cu-HAp4 exhibited good antibacterial activity, as evidenced by inhibition zone diameters of 0.9 mm for Escherichia coli and 0.8 mm for Staphylococcus aureus. These findings indicate that Mg and Cu-HAp effectively possess antibacterial properties. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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