| Autor: |
Chaudhary, Raj Lakshmi, Babu, Helena, Singh, SatguruSaran, Chandra, Shradha |
| Předmět: |
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| Zdroj: |
Journal of Cardiovascular Disease Research (Journal of Cardiovascular Disease Research); 2024, Vol. 15 Issue 7, p1481-1493, 13p |
| Abstrakt: |
Aim: To determine the effect of platelet rich plasma among patients undergoing type I tympanoplasty with and without topical use of platelet-rich Plasma (PRP) over the graft. Materials and Methods: A randomized, prospective, comparative study was conducted among 60 patients divided into two groups: Cases and control consisting of 30 patients each, having inactive mucosal Chronic otitis media who underwent type I tympanoplasty with the use of PRP for enhancing the graft uptake versus patients without use of PRP: 28 (93%) as compared to control 25(83%). Results: Preoperative and postoperative air-bone gap (A-B gap) was calculated at the end of 3 months and compared, and it was found to be statistically significantly better both in the case and control group (P < 0.05) and mean healing time of 4.64+/- 1.57 in cases in comparison to control group with mean healing time of 6.2+/-1.98. Conclusion: Our study shows that PRP is cheap, easy to prepare, autologous and cost effective. This platelet concentrate is enriched with various growth and healing factors, which helps in faster tympanic membrane closure following tympanoplasty and hence overall improving successful outcomes rate of tympanoplasty by preventing graft migration, with little to no perceivable side effects. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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