ASSOCIATION BETWEEN THYROID DYSFUNCTION AND DIABETIC NEPHROPATHY IN PATIENTS WITH TYPE 2 DIABETES MELLITUS.

Autor: soni, Ajay, Bansal, Dharam Prakash, Rijhwani, Puneet, soni, Paras Kumar, Sharma, Gunita, Kimmatkar, Utkarsh
Předmět:
Zdroj: Journal of Cardiovascular Disease Research (Journal of Cardiovascular Disease Research); 2024, Vol. 15 Issue 7, p2295-2300, 6p
Abstrakt: Introduction- Thyroid Dysfunction has been associated with type 2 diabetes mellitus (DM-2). However, it is not known whether common complications of DM-2 such as diabetic nephropathy, are also present with Thyroid Dysfunction. Aim- To study the association of Thyroid Dysfunction and diabetic nephropathy in patients with type 2 diabetes mellitus. Methodology-A Hospital based cross-sectional Observational study conducted in Mahatma Gandhi Medical College & Hospital, Jaipur, Rajasthan, India from September 2022 to August 2023 on 100 Patients with DM-2. Results- In present study the prevalence of thyroid dysfunction in DM-2 patients was 21%. In present study the prevalence of Subclinical Hypothyroidism (SCH) in DM-2 was 14%, the prevalence of Overt Hypothyroidism in DM-2 was 4%, the prevalence of Subclinical Hyperthyroidism in DM-2 was 1%, and the prevalence of Overt Hyperthyroidism in DM-2 was 2%. There were significant differences in term of Thyroid status in Diabetes patients with respect to Nephropathy i.e. prevalence of DN is higher in patients of DM with Thyroid dysfunction as compared to patients with euthyroid status (P = 0.027) . Conclusion-Thyroid Dysfunction may be independently associated with Diabetic Nephropathy in Indian patients with type 2 diabetes mellitus. This imply that Thyroid Dysfunction may be a new therapeutic target to prevent the development and progression of Diabetic Nephropathy in DM-2 patients. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index