| Autor: |
Mishra, Sunita, Janka, Janaki, Sahu, Aratiprava, Sahoo, Shyam Surat, Pradhan, Susajit Kumar |
| Předmět: |
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| Zdroj: |
Journal of Cardiovascular Disease Research (Journal of Cardiovascular Disease Research); 2024, Vol. 15 Issue 7, p1205-1221, 17p |
| Abstrakt: |
Background & aim Paravertebral block (PVB) is a commonly used technique, for postoperative analgesia after modified radical mastectomy(MRM).Though many adjuvants to bupivacaine in PVB have been tried for postoperative analgesia, none has been found ideal. We have compared the duration of analgesia in PVB using adjuvant like dexmedetomidine and nalbuphine with bupivacaine after MRM. Methods Sixtyfive female patients posted for MRM were divided into two groups. Group BN received ultrasound guided PVB with 20 ml bupivacaine 0.25% with nalbuphine 10mg and Group BD received 20 ml bupivacaine 0.25% with dexmedetomidine 1 μg/kg. After confirming PVB, surgery was done under general anesthesia in all patients. Time for 1st rescue analgesic request was the primary aim of our study. Secondary aim of our study was numerical rating scores (NRS) for pain at rest and on movement and total analgesic consumption. Side effects like nausea and vomiting,hemodynamics and sedation in post operative 24 hrs were also assessed. Results The time of the first rescue analgesic requirement was prolonged in the group BD (7.32 ± 1.75 hours) in contrary to group BN (4.94 ± 2.12 hours). The mean total paracetamol consumption as rescue analgesia in the in the first 24 hours postoperatively was significantly reduced in group BD (2.7 ±0.94 gm) in contrary to group BN (3.6 ± 0.98 gm). (p<0.001) Decrease in hear rate and mean arterial pressure was more in BD group compared to BN group intraoperatively. (p<0.001) Conclusion Dexmedetomidine provides prolonged analgesia when used as additive to bupivacaine in PVB for modified radical mastectomy compared to nalbuphine. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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